Drug Information

Drug General Information
Drug ID
D0K2HA
Former ID
DIB004789
Drug Name
PF-2413873
Synonyms
PF-02413873
Drug Type
Small molecular drug
Indication Endometriosis [ICD9: 617; ICD10:N80] Phase 1 [522505]
Company
Pfizer Inc
Formula
C18H21N3O3S
Canonical SMILES
C(#N)c1c(cc(cc1C)Oc1c(nn(c1C)CS(=O)(=O)C)C1CC1)C
PubChem Compound ID
16662425
Target and Pathway
Target(s) Progesterone receptor Target Info Antagonist [550034]
KEGG Pathway Oocyte meiosis
Progesterone-mediated oocyte maturation
Pathway Interaction Database Cellular roles of Anthrax toxin
Reactome Nuclear signaling by ERBB4
Nuclear Receptor transcription pathway
WikiPathways Ovarian Infertility Genes
Signaling by ERBB4
Nuclear Receptors
References
Ref 522505ClinicalTrials.gov (NCT00800618) A Study To Investigate How The Body Handles Multiple Doses Of PF-0243873 And To Investigate The Effect Of PF-02413873 On Sex Hormone Levels In Healthy Young Women. U.S. National Institutes of Health.
Ref 550034Unusual base-catalyzed exchange in the synthesis of deuterated PF-2413873. Journal of Labelled Compounds. 08/2009; 52(10):435 - 442.

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