Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D06QRW
|
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| Former ID |
DIB003873
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| Drug Name |
Lazabemide
|
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| Synonyms |
Lazabemine; Pakio; Tempium; Ro-19-6327; Ro-41-3776; Ro-19-6327/000
|
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| Drug Type |
Small molecular drug
|
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| Company |
Roche Holding AG
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| Formula |
C8H10ClN3O
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| InChI |
InChI=1S/C8H10ClN3O/c9-6-1-2-7(12-5-6)8(13)11-4-3-10/h1-2,5H,3-4,10H2,(H,11,13)
|
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| InChIKey |
JZXRLKWWVNUZRB-UHFFFAOYSA-N
|
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| PubChem Compound ID | |||||
| PubChem Substance ID |
7980091, 8194561, 15220005, 43127665, 47206517, 50064090, 50112873, 50460487, 57318127, 92729659, 103183900, 103831836, 103938836, 104350168, 117465703, 126424309, 128351763, 132555187, 134343054, 135028045, 137239417, 139290484, 139640715, 164814824, 178103253, 179149503, 184545911, 198970494, 224982470, 226493370, 252216705, 252351209, 252428934
|
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| Target and Pathway | |||||
| Target(s) | Amine oxidase [flavin-containing] B | Target Info | Inhibitor | [534569] | |
| KEGG Pathway | Glycine, serine and threonine metabolism | ||||
| Arginine and proline metabolism | |||||
| Histidine metabolism | |||||
| Tyrosine metabolism | |||||
| Phenylalanine metabolism | |||||
| Tryptophan metabolism | |||||
| Drug metabolism - cytochrome P450 | |||||
| Metabolic pathways | |||||
| Serotonergic synapse | |||||
| Dopaminergic synapse | |||||
| Cocaine addiction | |||||
| Amphetamine addiction | |||||
| Alcoholism | |||||
| Pathway Interaction Database | Alpha-synuclein signaling | ||||
| References | |||||
| Ref 541750 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6640). | ||||
| Ref 545650 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800004032) | ||||
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