Drug Information

Drug General Information
Drug ID
D01LYX
Former ID
DIB009619
Drug Name
Eptastigmine
Synonyms
Epiastigmine; Eptastigmine tartrate; Heptylstigmine tartrate; Heptyl-physostigmine; L-693487; MF-201
Drug Type
Small molecular drug
Indication Cognitive disorders [ICD9: 290-294, 294.0, 780.09, 780.9, 780.93; ICD10:F01-F07, F04, F05, R41.3] Phase 3 [526265]
Company
Consiglio Nazionale delle Ricerche
Formula
C21H33N3O2
Canonical SMILES
[C@]12([C@@H](N(c3c1cc(OC(=O)NCCCCCCC)cc3)C)N(CC2)C)C
PubChem Compound ID
65872
Target and Pathway
Target(s) Acetylcholinesterase Target Info Inhibitor [526265]
KEGG Pathway Glycerophospholipid metabolism
Cholinergic synapse
PANTHER Pathway Muscarinic acetylcholine receptor 1 and 3 signaling pathway
Muscarinic acetylcholine receptor 2 and 4 signaling pathway
Nicotinic acetylcholine receptor signaling pathway
Pathway Interaction Database ATF-2 transcription factor network
PathWhiz Pathway Phospholipid Biosynthesis
WikiPathways Monoamine Transport
Biogenic Amine Synthesis
Acetylcholine Synthesis
Integrated Pancreatic Cancer Pathway
References
Ref 526265Eptastigmine: ten years of pharmacology, toxicology, pharmacokinetic, and clinical studies. CNS Drug Rev. 2001 Winter;7(4):369-86.
Ref 526265Eptastigmine: ten years of pharmacology, toxicology, pharmacokinetic, and clinical studies. CNS Drug Rev. 2001 Winter;7(4):369-86.

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