Drug Information

Drug General Information
Drug ID
D02KRI
Former ID
DIB010205
Drug Name
Epristeride
Synonyms
Zariflo; ONO-9302; SKB-105657; SKF-105657
Drug Type
Small molecular drug
Indication Hirsutism [ICD9: 704.1; ICD10:L68.0] Phase 3 [529459]
Company
SmithKline Beecham plc
Formula
C25H37NO3
Canonical SMILES
[C@@]12([C@H]([C@H]3[C@@H]([C@@]4(C(=CC3)C=C(C(=O)O)CC4<br />)C)CC2)CC[C@@H]1C(=O)NC(C)(C)C)C
CAS Number
CAS 119169-78-7
PubChem Compound ID
68741
Target and Pathway
Target(s) 5-alpha reductase Target Info Inhibitor [531271]
References
Ref 529459Epristeride SmithKline Beecham. IDrugs. 1998 May;1(1):152-7.
Ref 531271Discovery of a novel hybrid from finasteride and epristeride as 5alpha-reductase inhibitor. Bioorg Med Chem Lett. 2011 Jan 1;21(1):475-8.

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