Drug Information

Drug General Information
Drug ID
D0YB4D
Former ID
DIB010408
Drug Name
Eldacimibe
Synonyms
ACA-147; WAY-ACA-147
Drug Type
Small molecular drug
Indication Hyperlipidaemia [ICD9: 272.0-272.4; ICD10:E78] Phase 2 [545522]
Company
Wyeth
Formula
C39H58N2O5
Canonical SMILES
C1(=C(N(Cc2ccc(CC(C)(C)C)cc2)CCCCCC)Nc2cc(c(c(C(C)(C)C)<br />c2)O)C(C)(C)C)C(=O)OC(OC1=O)(C)C
CAS Number
CAS 141993-70-6
PubChem Compound ID
170321
Target and Pathway
Target(s) Liver carboxylesterase Target Info Modulator [533663]
KEGG Pathway Drug metabolism - other enzymes
Metabolic pathways
Pathway Interaction Database E2F transcription factor network
WikiPathways NRF2 pathway
Nuclear Receptors Meta-Pathway
Heroin metabolism
Irinotecan Pathway
Fluoropyrimidine Activity
Phase I biotransformations, non P450
References
Ref 545522Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800003592)
Ref 533663Prospects for drug therapy for hyperlipoproteinaemia. Diabete Metab. 1995 Apr;21(2):139-46.

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