Drug Information

Drug General Information
Drug ID
D05SSJ
Former ID
DIB012094
Drug Name
Dotarizine
Synonyms
Dotarazine; FI-6020; FI-6026
Drug Type
Small molecular drug
Indication Migraine [ICD9: 346; ICD10:G43] Terminated [525748]
Company
Ferrer Internacional SA
Formula
C29H34N2O2
Canonical SMILES
C1(OCCO1)(c1ccccc1)CCCN1CCN(C(c2ccccc2)c2ccccc2)CC1
CAS Number
CAS 84625-59-2
PubChem Compound ID
55285
Target and Pathway
Target(s) 5-HT 2 receptor Target Info Modulator [525748]
KEGG Pathway Calcium signaling pathway
Neuroactive ligand-receptor interaction
Gap junction
Serotonergic synapse
Inflammatory mediator regulation of TRP channels
References
Ref 525748Vasostabilizing effect of Dotarizine (Ca(2+)-channel blocker) on cerebrovascular reactivity in rabbits. Neurol Res. 2000 Mar;22(2):229-32.
Ref 525748Vasostabilizing effect of Dotarizine (Ca(2+)-channel blocker) on cerebrovascular reactivity in rabbits. Neurol Res. 2000 Mar;22(2):229-32.

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