Drug Information

Drug General Information
Drug ID
D0H7AV
Former ID
DIB003538
Drug Name
Pilsicainide
Synonyms
SUNRYTHM; Sunrhythm; Pilsicainide hydrochloride; DU-6552; SUN-1165; SUN-1165i
Drug Type
Small molecular drug
Indication Heart arrhythmia [ICD10:I47-I49] Approved [551871]
Company
Suntory Ltd
Formula
C17H25ClN2O
Canonical SMILES
C12(CC(=O)Nc3c(cccc3C)C)N(CCC1)CCC2
PubChem Compound ID
114817
Target and Pathway
Target(s) Sodium channel Target Info Modulator [531607], [551871]
KEGG Pathway Dopaminergic synapse
Reactome Interaction between L1 and Ankyrins
References
Ref 551871Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015
Ref 531607A sodium channel blocker, pilsicainide, produces atrial post-repolarization refractoriness through the reduction of sodium channel availability. Tohoku J Exp Med. 2011;225(1):35-42.
Ref 551871Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015

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