Drug Information

Drug General Information
Drug ID
D0F6GV
Former ID
DIB015514
Drug Name
Perospirone
Synonyms
Lullan; SM-9018
Drug Type
Small molecular drug
Indication Psychotic disorders [ICD9: 290-299; ICD10:F20-F29] Approved [542556], [551871]
Company
Sumitomo Pharmaceuticals Co Ltd
Formula
C23H30N4O2S
InChI
InChI=1S/C23H30N4O2S/c28-22-17-7-1-2-8-18(17)23(29)27(22)12-6-5-11-25-13-15-26(16-14-25)21-19-9-3-4-10-20(19)30-24-21/h3-4,9-10,17-18H,1-2,5-8,11-16H2/t17-,18+
InChIKey
FBVFZWUMDDXLLG-HDICACEKSA-N
PubChem Compound ID
115368
PubChem Substance ID
10236756, 14880639, 14880640, 26757988, 29296855, 57339138, 78381043, 104398210, 131275787, 131299841, 135107371, 139230895, 162181143, 175612202, 179149778, 184664953, 188932357, 198937425, 206246150, 223365892, 223573613, 226492169, 252355842, 252355843, 252432375, 252818162
Target and Pathway
Target(s) 5-HT 2 receptor Target Info Modulator [533697], [551871]
KEGG Pathway Calcium signaling pathway
Neuroactive ligand-receptor interaction
Gap junction
Serotonergic synapse
Inflammatory mediator regulation of TRP channels
References
Ref 542556(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7556).
Ref 551871Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015
Ref 533697Pharmacological effects of zotepine and other antipsychotics on the central 5-HT2 receptors. Pharmacopsychiatry. 1993 Mar;26(2):53-8.
Ref 551871Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015

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