Drug Information

Drug General Information
Drug ID
D06NXK
Former ID
DNC010924
Drug Name
(R)-6-(2-(2-methylpyrrolidin-1-yl)ethyl)quinoline
Drug Type
Small molecular drug
Indication Discovery agent Investigative [530904]
Formula
C16H20N2
Canonical SMILES
CC1CCCN1CCC2=CC3=C(C=C2)N=CC=C3
InChI
1S/C16H20N2/c1-13-4-3-10-18(13)11-8-14-6-7-16-15(12-14)5-2-9-17-16/h2,5-7,9,12-13H,3-4,8,10-11H2,1H3/t13-/m1/s1
InChIKey
HUQYUKHHFHNJRR-CYBMUJFWSA-N
PubChem Compound ID
46890563
Target and Pathway
Target(s) Potassium voltage-gated channel subfamily H member 2 Target Info Inhibitor [530904]
Histamine H3 receptor Target Info Inhibitor [530904]
KEGG Pathway Neuroactive ligand-receptor interaction
PathWhiz Pathway Muscle/Heart Contraction
Reactome Voltage gated Potassium channelsR-HSA-390650:Histamine receptors
G alpha (i) signalling events
WikiPathways SIDS Susceptibility Pathways
Hematopoietic Stem Cell Differentiation
Potassium ChannelsWP727:Monoamine Transport
GPCRs, Class A Rhodopsin-like
GPCR ligand binding
GPCR downstream signaling
References
Ref 530904Bioorg Med Chem Lett. 2010 Jun 1;20(11):3295-300. Epub 2010 Apr 18.In vitro studies on a class of quinoline containing histamine H3 antagonists.
Ref 530904Bioorg Med Chem Lett. 2010 Jun 1;20(11):3295-300. Epub 2010 Apr 18.In vitro studies on a class of quinoline containing histamine H3 antagonists.

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