Drug Information

Drug General Information
Drug ID
D0J9VP
Former ID
DNC011549
Drug Name
3-tert-Butyl-3-ethyl-dihydro-furan-2-one
Drug Type
Small molecular drug
Indication Discovery agent Investigative [533975]
Formula
C10H18O2
Canonical SMILES
CCC1(CCOC1=O)C(C)(C)C
InChI
1S/C10H18O2/c1-5-10(9(2,3)4)6-7-12-8(10)11/h5-7H2,1-4H3
InChIKey
LHTNJLBXDQITGL-UHFFFAOYSA-N
PubChem Compound ID
10261531
Target and Pathway
Target(s) Gamma-aminobutyric acid receptor subunit alpha-1 Target Info Inhibitor [533975]
Gamma-aminobutyric acid receptor subunit gamma-2 Target Info Inhibitor [533975]
Gamma-aminobutyric acid receptor Target Info Inhibitor [533975]
Gamma-aminobutyric acid receptor subunit beta-2 Target Info Inhibitor [533975]
KEGG Pathway Neuroactive ligand-receptor interaction
Retrograde endocannabinoid signaling
GABAergic synapse
Morphine addiction
Nicotine addictionhsa04080:Neuroactive ligand-receptor interaction
Serotonergic synapse
Nicotine addiction
Reactome Ligand-gated ion channel transport
GABA A receptor activationR-HSA-975298:Ligand-gated ion channel transport
GABA A receptor activation
WikiPathways SIDS Susceptibility Pathways
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
Iron uptake and transportWP2754:Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
Iron uptake and transport
References
Ref 533975J Med Chem. 1994 Jan 21;37(2):275-86.Alpha-spirocyclopentyl- and alpha-spirocyclopropyl-gamma-butyrolactones: conformationally constrained derivatives of anticonvulsant and convulsant alpha,alpha-disubstituted gamma-butyrolactones.
Ref 533975J Med Chem. 1994 Jan 21;37(2):275-86.Alpha-spirocyclopentyl- and alpha-spirocyclopropyl-gamma-butyrolactones: conformationally constrained derivatives of anticonvulsant and convulsant alpha,alpha-disubstituted gamma-butyrolactones.

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