Drug Information

Drug General Information
Drug ID
D07MRF
Former ID
DNC012344
Drug Name
3-Nitro-9H-beta-carboline
Drug Type
Small molecular drug
Indication Discovery agent Investigative [533363]
Formula
C11H7N3O2
Canonical SMILES
C1=CC=C2C(=C1)C3=CC(=NC=C3N2)[N+](=O)[O-]
InChI
1S/C11H7N3O2/c15-14(16)11-5-8-7-3-1-2-4-9(7)13-10(8)6-12-11/h1-6,13H
InChIKey
XQNOYQREYCKAIN-UHFFFAOYSA-N
PubChem Compound ID
4713455
Target and Pathway
Target(s) Gamma-aminobutyric acid receptor Target Info Inhibitor [533363]
Gamma-aminobutyric acid receptor subunit alpha-1 Target Info Inhibitor [533363]
KEGG Pathway Neuroactive ligand-receptor interaction
Retrograde endocannabinoid signaling
GABAergic synapse
Morphine addiction
Nicotine addiction
Reactome Ligand-gated ion channel transport
GABA A receptor activation
WikiPathways SIDS Susceptibility Pathways
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
Iron uptake and transport
References
Ref 533363J Med Chem. 1988 Sep;31(9):1854-61.Synthesis of novel 3-substituted beta-carbolines as benzodiazepine receptor ligands: probing the benzodiazepine receptor pharmacophore.
Ref 533363J Med Chem. 1988 Sep;31(9):1854-61.Synthesis of novel 3-substituted beta-carbolines as benzodiazepine receptor ligands: probing the benzodiazepine receptor pharmacophore.

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