TTD | Drug: D04YWX

Drug General Information
Drug ID	D04YWX
Former ID	DIB020881
Drug Name	S22153
Synonyms	S 22153; S-22153
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[538839]
Formula	C14H17NOS
InChI	InChI=1S/C14H17NOS/c1-3-11-4-5-14-13(8-11)12(9-17-14)6-7-15-10(2)16/h4-5,8-9H,3,6-7H2,1-2H3,(H,15,16)
InChIKey	PICRXJDULXLJCZ-UHFFFAOYSA-N
PubChem Compound ID	9816339
PubChem Substance ID	14774241, 24120858, 44852307, 77923906, 85221853, 135650965, 163772447, 228088996, 248948511
Target and Pathway
Target(s)	Melatonin receptor	Target Info	Antagonist	[526629]
KEGG Pathway	Neuroactive ligand-receptor interaction
KEGG Pathway	Circadian entrainment
Reactome	Class A/1 (Rhodopsin-like receptors)
Reactome	G alpha (i) signalling events
WikiPathways	GPCRs, Class A Rhodopsin-like
	Small Ligand GPCRs
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 538839	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 1361).
Ref 526629	New selective ligands of human cloned melatonin MT1 and MT2 receptors. Naunyn Schmiedebergs Arch Pharmacol. 2003 Jun;367(6):553-61. Epub 2003 May 23.

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Drug Information