Drug Information

Drug General Information
Drug ID
D0V2QF
Former ID
DNC000080
Drug Name
5'-deoxy-5'-[(3-hydrazinopropyl)methylamino]adenosine
Drug Type
Small molecular drug
Indication Discovery agent Investigative [535793]
Formula
C14H24N8O3
Canonical SMILES
CN(CCCNN)CC1C(C(C(O1)N2C=NC3=C2N=CN=C3N)O)O
InChI
1S/C14H24N8O3/c1-21(4-2-3-20-16)5-8-10(23)11(24)14(25-8)22-7-19-9-12(15)17-6-18-13(9)22/h6-8,10-11,14,20,23-24H,2-5,16H2,1H3,(H2,15,17,18)/t8-,10-,11-,14-/m1/s1
InChIKey
MYNRDUPGBPOWQT-IDTAVKCVSA-N
CAS Number
CAS 112621-42-8
PubChem Compound ID
122092
PubChem Substance ID
596146, 7888924, 15447468, 29302543, 51735489, 57339947, 99350550, 104415000, 128666342, 135079812, 162776217, 227212535
Target and Pathway
Target(s) S-adenosylmethioninedecarboxylase proenzyme Target Info Inhibitor [535793]
Lactosylceramide alpha-2,3-sialyltransferase Target Info Inhibitor [535793]
BioCyc Pathway Methionine salvage cycle III
Spermine biosynthesis
Spermidine biosynthesis
KEGG Pathway Cysteine and methionine metabolism
Arginine and proline metabolism
Metabolic pathwayshsa00604:Glycosphingolipid biosynthesis - ganglio series
Metabolic pathways
NetPath Pathway EGFR1 Signaling Pathway
PathWhiz Pathway Spermidine and Spermine Biosynthesis
Methionine Metabolism
Reactome Sialic acid metabolism
WikiPathways Metabolism of amino acids and derivativesWP1423:Ganglio Sphingolipid Metabolism
References
Ref 535793S-adenosylmethionine decarboxylase as an enzyme target for therapy. Pharmacol Ther. 1992 Dec;56(3):359-77.
Ref 535793S-adenosylmethionine decarboxylase as an enzyme target for therapy. Pharmacol Ther. 1992 Dec;56(3):359-77.

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