Drug Information

Drug General Information
Drug ID
D06DTT
Former ID
DNC012598
Drug Name
RO-054520
Drug Type
Small molecular drug
Indication Discovery agent Investigative [533368]
Formula
C16H13FN2O
Canonical SMILES
CN1C(=O)CN=C(C2=CC=CC=C21)C3=CC=CC=C3F
InChI
1S/C16H13FN2O/c1-19-14-9-5-3-7-12(14)16(18-10-15(19)20)11-6-2-4-8-13(11)17/h2-9H,10H2,1H3
InChIKey
YVTVBCWQHDDTGB-UHFFFAOYSA-N
PubChem Compound ID
193319
Target and Pathway
Target(s) Gamma-aminobutyric acid receptor subunit alpha-1 Target Info Inhibitor [533368]
Gamma-aminobutyric acid receptor Target Info Inhibitor [533368]
KEGG Pathway Neuroactive ligand-receptor interaction
Retrograde endocannabinoid signaling
GABAergic synapse
Morphine addiction
Nicotine addiction
Reactome Ligand-gated ion channel transport
GABA A receptor activation
WikiPathways SIDS Susceptibility Pathways
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
Iron uptake and transport
References
Ref 533368J Med Chem. 1988 Dec;31(12):2235-46.Methods for drug discovery: development of potent, selective, orally effective cholecystokinin antagonists.
Ref 533368J Med Chem. 1988 Dec;31(12):2235-46.Methods for drug discovery: development of potent, selective, orally effective cholecystokinin antagonists.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Tang and Dr. Zhang.