Drug Information

Drug General Information
Drug ID
D0OY8Y
Former ID
DIB021113
Drug Name
UCM 549
Synonyms
UCM-549; UCM549
Drug Type
Small molecular drug
Indication Discovery agent Investigative [542724]
Formula
C19H21NO2
InChI
InChI=1S/C19H21NO2/c1-13(21)20-12-17-10-15-6-4-3-5-14(15)9-16-7-8-18(22-2)11-19(16)17/h3-8,11,17H,9-10,12H2,1-2H3,(H,20,21)
InChIKey
PQZZGTZTKGECDT-UHFFFAOYSA-N
PubChem Compound ID
11185529
PubChem Substance ID
16266406, 23374839, 42265224, 77436768, 103454488, 103923936, 223366105, 246989492
Target and Pathway
Target(s) Melatonin receptor Target Info Antagonist [529075]
KEGG Pathway Neuroactive ligand-receptor interaction
Circadian entrainment
Reactome Class A/1 (Rhodopsin-like receptors)
G alpha (i) signalling events
WikiPathways GPCRs, Class A Rhodopsin-like
Small Ligand GPCRs
GPCR ligand binding
GPCR downstream signaling
References
Ref 542724(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7772).
Ref 529075Synthesis, enantiomeric resolution, and structure-activity relationship study of a series of 10,11-dihydro-5H-dibenzo[a,d]cycloheptene MT2 receptor antagonists. ChemMedChem. 2007 Dec;2(12):1741-9.

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