Drug Information

Drug General Information
Drug ID
D03ZPH
Former ID
DIB018483
Drug Name
15-deoxy-Delta12,14-PGD2
Synonyms
15-deoxy-Delta12,14-prostaglandin D2; 15d-Delta12,14-PGD2
Drug Type
Small molecular drug
Indication Discovery agent Investigative [539205]
Formula
C20H30O4
InChI
InChI=1S/C20H30O4/c1-2-3-4-5-6-9-12-16-17(19(22)15-18(16)21)13-10-7-8-11-14-20(23)24/h6-7,9-10,12,17,19,22H,2-5,8,11,13-15H2,1H3,(H,23,24)/b9-6+,10-7-,16-12+/t17-,19+/m1/s1
InChIKey
QUGBPWLPAUHDTI-PLGLXCLHSA-N
PubChem Compound ID
5283052
PubChem Substance ID
4265985, 11038709, 39316469, 51937931, 57358821, 103420736, 113858952, 135651376, 179656220, 252457431
Target and Pathway
Target(s) Putative G-protein coupled receptor 44 Target Info Agonist [526611]
Reactome Prostanoid ligand receptors
G alpha (i) signalling events
WikiPathways GPCRs, Class A Rhodopsin-like
GPCR ligand binding
GPCR downstream signaling
References
Ref 539205(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 1904).
Ref 526611Expression and molecular pharmacology of the mouse CRTH2 receptor. J Pharmacol Exp Ther. 2003 Aug;306(2):463-70. Epub 2003 Apr 29.

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