Drug Information

Drug General Information
Drug ID
D00TRF
Former ID
DNC007393
Drug Name
2-(benzyloxyamino)-N-hydroxyacetamide
Drug Type
Small molecular drug
Indication Discovery agent Investigative [528653]
Formula
C9H12N2O3
Canonical SMILES
C1=CC=C(C=C1)CONCC(=O)NO
InChI
1S/C9H12N2O3/c12-9(11-13)6-10-14-7-8-4-2-1-3-5-8/h1-5,10,13H,6-7H2,(H,11,12)
InChIKey
PMVJGZGFFBJYLQ-UHFFFAOYSA-N
PubChem Compound ID
44423683
Target and Pathway
Target(s) Carbonic anhydrase IX Target Info Inhibitor [528653]
KEGG Pathway Nitrogen metabolism
Pathway Interaction Database HIF-1-alpha transcription factor network
Reactome Regulation of gene expression by Hypoxia-inducible Factor
Reversible hydration of carbon dioxide
WikiPathways Vitamin D Receptor Pathway
Reversible Hydration of Carbon Dioxide
Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
References
Ref 528653Bioorg Med Chem. 2007 Mar 15;15(6):2298-311. Epub 2007 Jan 19.Carbonic anhydrase and matrix metalloproteinase inhibitors. Inhibition of human tumor-associated isozymes IX and cytosolic isozyme I andII with sulfonylated hydroxamates.
Ref 528653Bioorg Med Chem. 2007 Mar 15;15(6):2298-311. Epub 2007 Jan 19.Carbonic anhydrase and matrix metalloproteinase inhibitors. Inhibition of human tumor-associated isozymes IX and cytosolic isozyme I andII with sulfonylated hydroxamates.

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