Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D09UWI
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| Former ID |
DNC006304
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| Drug Name |
2,5-bis(4-Hydroxyphenyl)thiophene
|
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| Drug Type |
Small molecular drug
|
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| Indication | Discovery agent | Investigative | [527907] | ||
| Formula |
C16H12O2S
|
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| Canonical SMILES |
C1=CC(=CC=C1C2=CC=C(S2)C3=CC=C(C=C3)O)O
|
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| InChI |
1S/C16H12O2S/c17-13-5-1-11(2-6-13)15-9-10-16(19-15)12-3-7-14(18)8-4-12/h1-10,17-18H
|
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| InChIKey |
KZMOBYGIRBRCFV-UHFFFAOYSA-N
|
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Amyloid beta A4 protein | Target Info | Inhibitor | [527907] | |
| KEGG Pathway | Notch signaling pathway | ||||
| Alzheimer's disease | |||||
| Reactome | Nuclear signaling by ERBB4 | ||||
| Degradation of the extracellular matrix | |||||
| Regulated proteolysis of p75NTR | |||||
| NRIF signals cell death from the nucleus | |||||
| Activated NOTCH1 Transmits Signal to the Nucleus | |||||
| Constitutive Signaling by NOTCH1 PEST Domain Mutants | |||||
| Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants | |||||
| EPH-ephrin mediated repulsion of cells | |||||
| References | |||||
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