Drug Information

Drug General Information
Drug ID
D0B1QM
Former ID
DIB019997
Drug Name
HC067047
Synonyms
HC 067047
Drug Type
Small molecular drug
Indication Discovery agent Investigative [467548]
Formula
C26H28F3N3O2
InChI
InChI=1S/C26H28F3N3O2/c1-19-23(25(33)30-22-10-5-9-21(17-22)26(27,28)29)18-24(20-7-3-2-4-8-20)32(19)12-6-11-31-13-15-34-16-14-31/h2-5,7-10,17-18H,6,11-16H2,1H3,(H,30,33)
InChIKey
NCZYSQOTAYFTNM-UHFFFAOYSA-N
PubChem Compound ID
2742550
PubChem Substance ID
3166908, 4421111, 8801816, 30100042, 61541497, 79034556, 89773283, 111379662, 125790701, 137276058, 163124717, 165241792, 172088883, 178101030, 204371511, 223705419, 240325216, 241376807, 242553148, 252157783, 252450843
Target and Pathway
Target(s) Transient receptor potential cation channel subfamily V member 4 Target Info Blocker (channel blocker) [531222]
KEGG Pathway Inflammatory mediator regulation of TRP channels
Reactome TRP channels
References
Ref 467548(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4213).
Ref 531222Inhibition of the cation channel TRPV4 improves bladder function in mice and rats with cyclophosphamide-induced cystitis. Proc Natl Acad Sci U S A. 2010 Nov 2;107(44):19084-9.

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