Drug Information

Drug General Information
Drug ID
D0X4EV
Former ID
DNC003706
Drug Name
8-Chloro-1,2,3,4-tetrahydro-acridin-9-ylamine
Drug Type
Small molecular drug
Indication Discovery agent Investigative [551237]
Formula
C13H13ClN2
Canonical SMILES
C1CCC2=NC3=C(C(=CC=C3)Cl)C(=C2C1)N
InChI
1S/C13H13ClN2/c14-9-5-3-7-11-12(9)13(15)8-4-1-2-6-10(8)16-11/h3,5,7H,1-2,4,6H2,(H2,15,16)
InChIKey
KVGMGGLTJLJDFE-UHFFFAOYSA-N
PubChem Compound ID
19770285
Target and Pathway
Target(s) Acetylcholinesterase Target Info Inhibitor [551237]
KEGG Pathway Glycerophospholipid metabolism
Cholinergic synapse
PANTHER Pathway Muscarinic acetylcholine receptor 1 and 3 signaling pathway
Muscarinic acetylcholine receptor 2 and 4 signaling pathway
Nicotinic acetylcholine receptor signaling pathway
Pathway Interaction Database ATF-2 transcription factor network
PathWhiz Pathway Phospholipid Biosynthesis
WikiPathways Monoamine Transport
Biogenic Amine Synthesis
Acetylcholine Synthesis
Integrated Pancreatic Cancer Pathway
References
Ref 551237The synthesis and in vitro acetylcholinesterase and butyrylcholinesterase inhibitory activity of tacrine (Cognex?) derivaties, Bioorg. Med. Chem. Lett. 2(8):861-864 (1992).
Ref 551237The synthesis and in vitro acetylcholinesterase and butyrylcholinesterase inhibitory activity of tacrine (Cognex?) derivaties, Bioorg. Med. Chem. Lett. 2(8):861-864 (1992).

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