Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0O5FK
|
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| Former ID |
DNC006476
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| Drug Name |
2-(4-(methylamino)phenyl)benzo[d]thiazol-6-ol
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| Drug Type |
Small molecular drug
|
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| Indication | Discovery agent | Investigative | [528161] | ||
| Formula |
C14H12N2OS
|
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| Canonical SMILES |
CNC1=CC=C(C=C1)C2=NC3=C(S2)C=C(C=C3)O
|
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| InChI |
1S/C14H12N2OS/c1-15-10-4-2-9(3-5-10)14-16-12-7-6-11(17)8-13(12)18-14/h2-8,15,17H,1H3
|
||||
| InChIKey |
ZQAQXZBSGZUUNL-UHFFFAOYSA-N
|
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Amyloid beta A4 protein | Target Info | Inhibitor | [528161] | |
| KEGG Pathway | Notch signaling pathway | ||||
| Alzheimer's disease | |||||
| Reactome | Nuclear signaling by ERBB4 | ||||
| Degradation of the extracellular matrix | |||||
| Regulated proteolysis of p75NTR | |||||
| NRIF signals cell death from the nucleus | |||||
| Activated NOTCH1 Transmits Signal to the Nucleus | |||||
| Constitutive Signaling by NOTCH1 PEST Domain Mutants | |||||
| Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants | |||||
| EPH-ephrin mediated repulsion of cells | |||||
| References | |||||
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