TTD | Drug: D03OYD

Drug General Information
Drug ID	D03OYD
Former ID	DIB018474
Drug Name	13,14-dihydro-16-m-chlorophenoxy-w-tetranor-PGF1alpha
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[539252]
Formula	C22H33ClO6
InChI	InChI=1S/C22H33ClO6/c23-15-6-5-7-17(12-15)29-14-16(24)10-11-19-18(20(25)13-21(19)26)8-3-1-2-4-9-22(27)28/h5-7,12,16,18-21,24-26H,1-4,8-11,13-14H2,(H,27,28)/t16-,18-,19-,20+,21-/m1/s1
InChIKey	XECZBZWECQIBDA-LELZANKISA-N
PubChem Compound ID	5311240
PubChem Substance ID	7979769, 15056658, 39340948, 50957595, 103214704, 103985321, 114155643, 129675921, 135649649, 140326510
Target and Pathway
Target(s)	Prostaglandin F2-alpha receptor	Target Info	Agonist	[525721]
KEGG Pathway	Calcium signaling pathway
KEGG Pathway	Neuroactive ligand-receptor interaction
Reactome	Prostanoid ligand receptors
Reactome	G alpha (q) signalling events
WikiPathways	Prostaglandin Synthesis and Regulation
	GPCRs, Class A Rhodopsin-like
	Gastrin-CREB signalling pathway via PKC and MAPK
	Small Ligand GPCRs
	GPCR ligand binding
	GPCR downstream signaling
	GPCRs, Other
References
Ref 539252	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 1955).
Ref 525721	J Med Chem. 2000 Mar 9;43(5):945-52.Design and synthesis of 13,14-dihydro prostaglandin F(1alpha) analogues as potent and selective ligands for the human FP receptor.

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Drug Information