Drug Information

Drug General Information
Drug ID
D02HEK
Former ID
DNC011526
Drug Name
1-(9H-beta-Carbolin-3-yl)-ethanone
Drug Type
Small molecular drug
Indication Discovery agent Investigative [533414]
Formula
C13H10N2O
Canonical SMILES
CC(=O)C1=NC=C2C(=C1)C3=CC=CC=C3N2
InChI
1S/C13H10N2O/c1-8(16)12-6-10-9-4-2-3-5-11(9)15-13(10)7-14-12/h2-7,15H,1H3
InChIKey
MPLXFBXMWYMAFN-UHFFFAOYSA-N
PubChem Compound ID
12789146
Target and Pathway
Target(s) Gamma-aminobutyric acid receptor subunit alpha-1 Target Info Inhibitor [533414]
Gamma-aminobutyric acid receptor Target Info Inhibitor [533414]
KEGG Pathway Neuroactive ligand-receptor interaction
Retrograde endocannabinoid signaling
GABAergic synapse
Morphine addiction
Nicotine addiction
Reactome Ligand-gated ion channel transport
GABA A receptor activation
WikiPathways SIDS Susceptibility Pathways
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
Iron uptake and transport
References
Ref 533414J Med Chem. 1987 Apr;30(4):750-3.Synthesis of 6-substituted beta-carbolines that behave as benzodiazepine receptor antagonists or inverse agonists.
Ref 533414J Med Chem. 1987 Apr;30(4):750-3.Synthesis of 6-substituted beta-carbolines that behave as benzodiazepine receptor antagonists or inverse agonists.

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