Drug Information

Drug General Information
Drug ID
D03DGZ
Former ID
DCL000689
Drug Name
Alphagen
Drug Type
Small molecular drug
Indication Chronic obstructive pulmonary disease; Cystic fibrosis [ICD9: 277.0, 460-519, 490-492, 494-496, 709.2; ICD10:E84, J00-J99, J40-J44, J47, L90.5] Phase 1 [536223]
Company
GeneRx+
Formula
C23H30ClN
Canonical SMILES
CCC(CC=CC1=CC=CC=C1)(C2=CC=CC=C2)N(C)CC3CC3.Cl
InChI
1S/C23H29N.ClH/c1-3-23(22-14-8-5-9-15-22,24(2)19-21-16-17-21)18-10-13-20-11-6-4-7-12-20;/h4-15,21H,3,16-19H2,1-2H3;1H/b13-10+;
InChIKey
SCHQQPAJNUHKSV-RSGUCCNWSA-N
CAS Number
CAS 140850-73-3
PubChem Compound ID
6438339
PubChem Substance ID
11968035, 12014707, 14925706, 43031347, 47206350, 49880389, 49880390, 50928221, 57367998, 114555869, 134223494, 134339199, 135078384, 160687145, 198965625, 232988894, 232992541, 241375887, 249617543, 252156450
Target and Pathway
Target(s) Alpha-1-antitrypsin Target Info Modulator [536223]
KEGG Pathway Complement and coagulation cascades
NetPath Pathway IL6 Signaling Pathway
PANTHER Pathway Blood coagulation
Pathway Interaction Database p73 transcription factor network
FOXA1 transcription factor network
Reactome Platelet degranulation
COPII (Coat Protein 2) Mediated Vesicle Transport
Cargo concentration in the ER
WikiPathways Complement and Coagulation Cascades
NRF2 pathway
Nuclear Receptors Meta-Pathway
References
Ref 536223Emerging drugs for the treatment of chronic obstructive pulmonary disease. Expert Opin Emerg Drugs. 2006 May;11(2):275-91.
Ref 536223Emerging drugs for the treatment of chronic obstructive pulmonary disease. Expert Opin Emerg Drugs. 2006 May;11(2):275-91.

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