Drug Information

Drug General Information
Drug ID
D03LFR
Former ID
DCL000392
Drug Name
SB-756050
Indication Type 2 diabetes [ICD9: 250; ICD10:E11] Discontinued in Phase 2 [548743]
Company
GlaxoSmithKline
Target and Pathway
Target(s) Bile acid receptor Target Info Agonist [550963]
KEGG Pathway Bile secretion
Pathway Interaction Database RXR and RAR heterodimerization with other nuclear receptor
Reactome Recycling of bile acids and salts
PPARA activates gene expression
Endogenous sterols
WikiPathways Nuclear Receptors in Lipid Metabolism and Toxicity
Nuclear Receptors Meta-Pathway
Farnesoid X Receptor Pathway
Drug Induction of Bile Acid Pathway
References
Ref 548743Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800028284)
Ref 550963Clinical pipeline report, company report or official report of GlaxoSmithKline (2009).

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