Drug Information

Drug General Information
Drug ID
D01IJD
Former ID
DIB018784
Drug Name
AH13205
Synonyms
AH 13205; AH-13205
Drug Type
Small molecular drug
Indication Discovery agent Investigative [539227]
Formula
C24H36O4
InChI
InChI=1S/C24H36O4/c1-2-3-6-10-22(25)19-14-12-18(13-15-19)20-16-17-23(26)21(20)9-7-4-5-8-11-24(27)28/h12-15,20-22,25H,2-11,16-17H2,1H3,(H,27,28)
InChIKey
XMQKDOCUWFCMEJ-UHFFFAOYSA-N
PubChem Compound ID
5310998
PubChem Substance ID
7978652, 11056197, 14878445, 39340731, 57359315, 74846342, 85208941, 114155013, 126437502, 135649907, 136351282, 141462592, 142864474, 162312713, 179293726, 230142758, 244391430
Target and Pathway
Target(s) Prostaglandin E2receptor, EP2 subtype Target Info Agonist [534478]
KEGG Pathway cAMP signaling pathway
Neuroactive ligand-receptor interaction
Inflammatory mediator regulation of TRP channels
Renin secretion
Pathways in cancer
Reactome Prostanoid ligand receptors
G alpha (s) signalling events
WikiPathways Prostaglandin Synthesis and Regulation
GPCRs, Class A Rhodopsin-like
Ovarian Infertility Genes
Small Ligand GPCRs
GPCR ligand binding
GPCR downstream signaling
References
Ref 539227(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 1928).
Ref 534478Ligand binding specificities of the eight types and subtypes of the mouse prostanoid receptors expressed in Chinese hamster ovary cells. Br J Pharmacol. 1997 Sep;122(2):217-24.

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