Drug Information

Drug General Information
Drug ID
D0R7UO
Former ID
DNC012675
Drug Name
5-Aminomethyl-3-pyrrol-1-yl-oxazolidin-2-one
Drug Type
Small molecular drug
Indication Discovery agent Investigative [526287]
Formula
C8H11N3O2
Canonical SMILES
C1C(OC(=O)N1N2C=CC=C2)CN
InChI
1S/C8H11N3O2/c9-5-7-6-11(8(12)13-7)10-3-1-2-4-10/h1-4,7H,5-6,9H2/t7-/m0/s1
InChIKey
OZSRSVNLPCHFKO-ZETCQYMHSA-N
PubChem Compound ID
10888544
Target and Pathway
Target(s) Amine oxidase [flavin-containing] B Target Info Inhibitor [526287]
BioCyc Pathway Superpathway of tryptophan utilization
Tryptophan degradation via tryptamine
Dopamine degradation
Putrescine degradation III
Noradrenaline and adrenaline degradation
KEGG Pathway Glycine, serine and threonine metabolism
Arginine and proline metabolism
Histidine metabolism
Tyrosine metabolism
Phenylalanine metabolism
Tryptophan metabolism
Drug metabolism - cytochrome P450
Metabolic pathways
Serotonergic synapse
Dopaminergic synapse
Cocaine addiction
Amphetamine addiction
Alcoholism
PANTHER Pathway Adrenaline and noradrenaline biosynthesis
5-Hydroxytryptamine degredation
Dopamine receptor mediated signaling pathway
Pathway Interaction Database Alpha-synuclein signaling
WikiPathways Tryptophan metabolism
Dopamine metabolism
Phase 1 - Functionalization of compounds
References
Ref 526287J Med Chem. 2002 Mar 14;45(6):1180-3.3-(1H-Pyrrol-1-yl)-2-oxazolidinones as reversible, highly potent, and selective inhibitors of monoamine oxidase type A.
Ref 526287J Med Chem. 2002 Mar 14;45(6):1180-3.3-(1H-Pyrrol-1-yl)-2-oxazolidinones as reversible, highly potent, and selective inhibitors of monoamine oxidase type A.

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