Drug Information

Drug General Information
Drug ID
D0F1ZX
Former ID
DNC013220
Drug Name
3-aminooxy-1-aminopropane
Drug Type
Small molecular drug
Indication Discovery agent Investigative [528522]
Formula
C3H10N2O
Canonical SMILES
C(CN)CON
InChI
1S/C3H10N2O/c4-2-1-3-6-5/h1-5H2
InChIKey
VSZFWDPIWSPZON-UHFFFAOYSA-N
PubChem Compound ID
65020
Target and Pathway
Target(s) Ornithine decarboxylase Target Info Inhibitor [528522]
BioCyc Pathway Putrescine biosynthesis I
NetPath Pathway TCR Signaling Pathway
IL2 Signaling Pathway
TGF_beta_Receptor Signaling Pathway
PANTHER Pathway Ornithine degradation
CCKR signaling map ST
Pathway Interaction Database Validated targets of C-MYC transcriptional activation
PathWhiz Pathway Spermidine and Spermine Biosynthesis
References
Ref 528522Antimicrob Agents Chemother. 2007 Feb;51(2):528-34. Epub 2006 Nov 13.Antileishmanial effect of 3-aminooxy-1-aminopropane is due to polyamine depletion.
Ref 528522Antimicrob Agents Chemother. 2007 Feb;51(2):528-34. Epub 2006 Nov 13.Antileishmanial effect of 3-aminooxy-1-aminopropane is due to polyamine depletion.

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