Drug Information

Drug General Information
Drug ID
D0HQ1I
Former ID
DNC014813
Drug Name
GNF-PF-85
Drug Type
Small molecular drug
Indication Discovery agent Investigative [529511]
Formula
C16H13N5O
Canonical SMILES
CC1=NC2=NC=NN2C(=C1)NC3=CC4=CC=CC=C4C=C3O
InChI
1S/C16H13N5O/c1-10-6-15(21-16(19-10)17-9-18-21)20-13-7-11-4-2-3-5-12(11)8-14(13)22/h2-9,20,22H,1H3
InChIKey
OMQCQQGZRWJBCI-UHFFFAOYSA-N
PubChem Compound ID
777193
Target and Pathway
Target(s) Dihydroorotate dehydrogenase, mitochondrial Target Info Inhibitor [529511]
KEGG Pathway Pyrimidine metabolism
Metabolic pathways
PathWhiz Pathway Pyrimidine Metabolism
Reactome Pyrimidine biosynthesis
WikiPathways Metabolism of nucleotides
References
Ref 529511J Med Chem. 2008 Jun 26;51(12):3649-53. Epub 2008 Jun 4.Triazolopyrimidine-based dihydroorotate dehydrogenase inhibitors with potent and selective activity against the malaria parasite Plasmodium falciparum.
Ref 529511J Med Chem. 2008 Jun 26;51(12):3649-53. Epub 2008 Jun 4.Triazolopyrimidine-based dihydroorotate dehydrogenase inhibitors with potent and selective activity against the malaria parasite Plasmodium falciparum.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Tang and Dr. Zhang.