Drug Information

Drug General Information
Drug ID
D0V7HJ
Former ID
DNC006797
Drug Name
3-[2-(N,N,N-trimethylammonium)ethoxy]pyridine
Drug Type
Small molecular drug
Indication Discovery agent Investigative [528245]
Formula
C10H17N2O+
Canonical SMILES
C[N+](C)(C)CCOC1=CN=CC=C1
InChI
1S/C10H17N2O/c1-12(2,3)7-8-13-10-5-4-6-11-9-10/h4-6,9H,7-8H2,1-3H3/q+1
InChIKey
WBRKKKJHXQZXEM-UHFFFAOYSA-N
PubChem Compound ID
9794401
Target and Pathway
Target(s) Neuronal acetylcholine receptor protein, beta-2 chain Target Info Inhibitor [528245]
Neuronal acetylcholine receptor protein, alpha-4 chain Target Info Inhibitor [528245]
KEGG Pathway Neuroactive ligand-receptor interaction
Cholinergic synapse
Nicotine addictionhsa04080:Neuroactive ligand-receptor interaction
Nicotine addiction
PANTHER Pathway Nicotinic acetylcholine receptor signaling pathway
Nicotine pharmacodynamics pathwayP00044:Nicotinic acetylcholine receptor signaling pathway
Nicotine pharmacodynamics pathway
Reactome Highly sodium permeable acetylcholine nicotinic receptors
Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
Highly calcium permeable nicotinic acetylcholine receptorsR-HSA-629587:Highly sodium permeable acetylcholine nicotinic receptors
Highly calcium permeable nicotinic acetylcholine receptors
WikiPathways SIDS Susceptibility Pathways
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
Nicotine Activity on Dopaminergic NeuronsWP706:SIDS Susceptibility Pathways
Nicotine Activity on Dopaminergic Neurons
References
Ref 528245Bioorg Med Chem Lett. 2006 Aug 15;16(16):4283-6. Epub 2006 Jun 9.Aryloxyethylamines: binding at alpha7 nicotinic acetylcholine receptors.
Ref 528245Bioorg Med Chem Lett. 2006 Aug 15;16(16):4283-6. Epub 2006 Jun 9.Aryloxyethylamines: binding at alpha7 nicotinic acetylcholine receptors.

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