Drug Information

Drug General Information
Drug ID
D0N9DU
Former ID
DIB020052
Drug Name
indirubin derivative E804
Synonyms
indirubin E804; compound 2 [PMID: 21632247]
Drug Type
Small molecular drug
Indication Discovery agent Investigative [531498]
Formula
C20H19N3O4
InChI
InChI=1S/C20H19N3O4/c24-11-12(25)9-10-27-23-18-14-6-2-4-8-16(14)21-19(18)17-13-5-1-3-7-15(13)22-20(17)26/h1-8,12,21,23-25H,9-11H2
InChIKey
CKLAPOFDFZKCPB-UHFFFAOYSA-N
PubChem Compound ID
6419764
PubChem Substance ID
10318992, 26758938, 43014030, 51352287, 53800899, 99302744, 114518102, 134444129, 163135203, 163687907, 175607488, 178102610, 208265109, 240219203
Target and Pathway
Target(s) Interferon-induced, double-stranded RNA-activated protein kinase Target Info Inhibitor [531498]
PANTHER Pathway Apoptosis signaling pathway
Pathway Interaction Database Signaling events mediated by TCPTP
Ceramide signaling pathway
PDGFR-beta signaling pathway
Reactome ISG15 antiviral mechanism
WikiPathways Type II interferon signaling (IFNG)
Host Interactions with Influenza Factors
Integrated Pancreatic Cancer Pathway
Translation Factors
References
Ref 531498Identification of new inhibitors of protein kinase R guided by statistical modeling. Bioorg Med Chem Lett. 2011 Jul 1;21(13):4108-14.
Ref 531498Identification of new inhibitors of protein kinase R guided by statistical modeling. Bioorg Med Chem Lett. 2011 Jul 1;21(13):4108-14.

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