Drug Information

Drug General Information
Drug ID
D08RPN
Former ID
DNC007631
Drug Name
(4-bromo-1H-pyrazol-1-yl)(m-tolyl)methanone
Drug Type
Small molecular drug
Indication Discovery agent Investigative [529037]
Formula
C11H9BrN2O
Canonical SMILES
CC1=CC=CC(=C1)C(=O)N2C=C(C=N2)Br
InChI
1S/C11H9BrN2O/c1-8-3-2-4-9(5-8)11(15)14-7-10(12)6-13-14/h2-7H,1H3
InChIKey
WACJMZOPBBWBAJ-UHFFFAOYSA-N
PubChem Compound ID
674653
Target and Pathway
Target(s) Leukocyte elastase Target Info Inhibitor [529037]
KEGG Pathway Transcriptional misregulation in cancer
Systemic lupus erythematosus
Pathway Interaction Database Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
C-MYB transcription factor network
Reactome Collagen degradation
Degradation of the extracellular matrix
Activation of Matrix Metalloproteinases
WikiPathways Hair Follicle Development: Cytodifferentiation (Part 3 of 3)
Human Complement System
Degradation of collagen
References
Ref 529037J Med Chem. 2007 Oct 4;50(20):4928-38. Epub 2007 Sep 12.N-benzoylpyrazoles are novel small-molecule inhibitors of human neutrophil elastase.
Ref 529037J Med Chem. 2007 Oct 4;50(20):4928-38. Epub 2007 Sep 12.N-benzoylpyrazoles are novel small-molecule inhibitors of human neutrophil elastase.

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