Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0E7LU
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| Former ID |
DIB018583
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| Drug Name |
3,5-DHPG
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| Synonyms |
3,5-dihydroxyphenylglycine
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent | Investigative | [538845] | ||
| Formula |
C8H9NO4
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| InChI |
InChI=1S/C8H9NO4/c9-7(8(12)13)4-1-5(10)3-6(11)2-4/h1-3,7,10-11H,9H2,(H,12,13)
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| InChIKey |
HOOWCUZPEFNHDT-UHFFFAOYSA-N
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| PubChem Compound ID | |||||
| PubChem Substance ID |
7724834, 10234545, 15120667, 26751684, 44436914, 50064450, 53788934, 57338377, 79707942, 85085469, 85208917, 91703835, 103811218, 103988486, 104380249, 117542958, 124879871, 128090722, 131304308, 132512948, 135066704, 135649729, 137088060, 162022565, 177748557, 179294194, 196362806, 225046176, 227716184, 241181626, 242084408, 249498318, 252160408
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| Target and Pathway | |||||
| Target(s) | Metabotropic glutamate receptor 5 | Target Info | Agonist | [525911] | |
| Metabotropicglutamate receptor 1 | Target Info | Agonist | [526599] | ||
| PANTHER Pathway | Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway | ||||
| Metabotropic glutamate receptor group III pathway | |||||
| Metabotropic glutamate receptor group I pathway | |||||
| Endogenous cannabinoid signalingP00027:Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway | |||||
| Endogenous cannabinoid signaling | |||||
| References | |||||
| Ref 525911 | Characterization of [(3)H]Quisqualate binding to recombinant rat metabotropic glutamate 1a and 5a receptors and to rat and human brain sections. J Neurochem. 2000 Dec;75(6):2590-601. | ||||
| Ref 526599 | [3H]R214127: a novel high-affinity radioligand for the mGlu1 receptor reveals a common binding site shared by multiple allosteric antagonists. Mol Pharmacol. 2003 May;63(5):1082-93. | ||||
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