Drug Information

Drug General Information
Drug ID
D06LIA
Former ID
DNC008171
Drug Name
N,4-dimethyl-3,4-dihydroquinazolin-2-amine
Drug Type
Small molecular drug
Indication Discovery agent Investigative [529158]
Formula
C10H13N3
Canonical SMILES
CC1C2=CC=CC=C2NC(=N1)NC
InChI
1S/C10H13N3/c1-7-8-5-3-4-6-9(8)13-10(11-2)12-7/h3-7H,1-2H3,(H2,11,12,13)
InChIKey
RSJLYEIETDMSCV-UHFFFAOYSA-N
PubChem Compound ID
44455897
Target and Pathway
Target(s) 5-hydroxytryptamine 5A receptor Target Info Inhibitor [529158]
KEGG Pathway Calcium signaling pathway
Neuroactive ligand-receptor interaction
Serotonergic synapse
PANTHER Pathway Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
Reactome Serotonin receptors
G alpha (i) signalling events
WikiPathways Monoamine GPCRs
GPCRs, Class A Rhodopsin-like
GPCR ligand binding
GPCR downstream signaling
References
Ref 529158Bioorg Med Chem Lett. 2008 Jan 1;18(1):262-6. Epub 2007 Oct 30.Cyclic guanidines as dual 5-HT5A/5-HT7 receptor ligands: optimising brain penetration.
Ref 529158Bioorg Med Chem Lett. 2008 Jan 1;18(1):262-6. Epub 2007 Oct 30.Cyclic guanidines as dual 5-HT5A/5-HT7 receptor ligands: optimising brain penetration.

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