Drug Information

Drug General Information
Drug ID
D0K2CZ
Former ID
DNC011590
Drug Name
1,1-Dimethyl-5-oxa-spiro[2.4]heptan-4-one
Drug Type
Small molecular drug
Indication Discovery agent Investigative [533975]
Formula
C8H12O2
Canonical SMILES
CC1(CC12CCOC2=O)C
InChI
1S/C8H12O2/c1-7(2)5-8(7)3-4-10-6(8)9/h3-5H2,1-2H3
InChIKey
KTGHZHGRFYRANW-UHFFFAOYSA-N
PubChem Compound ID
10464406
Target and Pathway
Target(s) Gamma-aminobutyric acid receptor subunit alpha-1 Target Info Inhibitor [533975]
Gamma-aminobutyric acid receptor Target Info Inhibitor [533975]
Gamma-aminobutyric acid receptor subunit gamma-2 Target Info Inhibitor [533975]
Gamma-aminobutyric acid receptor subunit beta-2 Target Info Inhibitor [533975]
KEGG Pathway Neuroactive ligand-receptor interaction
Retrograde endocannabinoid signaling
GABAergic synapse
Morphine addiction
Nicotine addictionhsa04080:Neuroactive ligand-receptor interaction
Serotonergic synapse
Nicotine addiction
Reactome Ligand-gated ion channel transport
GABA A receptor activationR-HSA-975298:Ligand-gated ion channel transport
GABA A receptor activation
WikiPathways SIDS Susceptibility Pathways
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
Iron uptake and transportWP2754:Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
Iron uptake and transport
References
Ref 533975J Med Chem. 1994 Jan 21;37(2):275-86.Alpha-spirocyclopentyl- and alpha-spirocyclopropyl-gamma-butyrolactones: conformationally constrained derivatives of anticonvulsant and convulsant alpha,alpha-disubstituted gamma-butyrolactones.
Ref 533975J Med Chem. 1994 Jan 21;37(2):275-86.Alpha-spirocyclopentyl- and alpha-spirocyclopropyl-gamma-butyrolactones: conformationally constrained derivatives of anticonvulsant and convulsant alpha,alpha-disubstituted gamma-butyrolactones.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Tang and Dr. Zhang.