Drug Information

Drug General Information
Drug ID
D0C9XD
Former ID
DIB020153
Drug Name
L-152,804
Synonyms
L-152804; L152804
Drug Type
Small molecular drug
Indication Discovery agent Investigative [538951]
Formula
C23H26O4
InChI
InChI=1S/C23H26O4/c1-22(2)9-14(24)20(15(25)10-22)19-13-7-5-6-8-17(13)27-18-12-23(3,4)11-16(26)21(18)19/h5-8,19,24H,9-12H2,1-4H3
InChIKey
CCJIUBMPDVWYLU-UHFFFAOYSA-N
PubChem Compound ID
624746
PubChem Substance ID
3337576, 5392252, 7856342, 8070748, 8701496, 14733964, 24316388, 43454562, 49930074, 75191849, 89157659, 92167244, 103596972, 104103991, 107075774, 109851035, 117935695, 118319542, 124623720, 124785223, 135650463, 142434098, 163135355, 170361561, 179117983, 250111136
Target and Pathway
Target(s) Neuropeptide Y receptor 5 Target Info Antagonist [525809]
KEGG Pathway Neuroactive ligand-receptor interaction
Reactome Peptide ligand-binding receptors
G alpha (i) signalling events
WikiPathways GPCRs, Class A Rhodopsin-like
Peptide GPCRs
GPCR ligand binding
GPCR downstream signaling
References
Ref 538951(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 1565).
Ref 525809L-152,804: orally active and selective neuropeptide Y Y5 receptor antagonist. Biochem Biophys Res Commun. 2000 May 27;272(1):169-73.

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