Drug Information

Drug General Information
Drug ID
D0T9WZ
Former ID
DIB019197
Drug Name
compound 10f
Drug Type
Small molecular drug
Indication Discovery agent Investigative [532680]
Formula
C23H15ClN2
InChI
InChI=1S/C23H15ClN2/c24-16-10-11-22-19(12-16)18(15-6-2-1-3-7-15)13-23(26-22)20-14-25-21-9-5-4-8-17(20)21/h1-14,25H
InChIKey
LTUZPODERZUPRD-UHFFFAOYSA-N
PubChem Compound ID
54613196
PubChem Substance ID
131407850, 194188482, 194947182, 252166803
Target and Pathway
Target(s) Bile-salt-activated lipase Target Info Inhibitor [532680]
Leukocyte elastase Target Info Inhibitor [532680]
BioCyc Pathway Triacylglycerol degradation
KEGG Pathway Transcriptional misregulation in cancer
Systemic lupus erythematosus
Pathway Interaction Database Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
C-MYB transcription factor network
Reactome Collagen degradation
Degradation of the extracellular matrix
Activation of Matrix Metalloproteinases
WikiPathways Lipid digestion, mobilization, and transportWP2840:Hair Follicle Development: Cytodifferentiation (Part 3 of 3)
Human Complement System
Degradation of collagen
References
Ref 532680Synthesis and evaluation of 2-(1H-indol-3-yl)-4-phenylquinolines as inhibitors of cholesterol esterase. Bioorg Med Chem Lett. 2014 Mar 15;24(6):1545-9.
Ref 532680Synthesis and evaluation of 2-(1H-indol-3-yl)-4-phenylquinolines as inhibitors of cholesterol esterase. Bioorg Med Chem Lett. 2014 Mar 15;24(6):1545-9.

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