Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D03THP
|
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| Former ID |
DNC006300
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| Drug Name |
4-(5-(4-methoxyphenyl)thiophen-2-yl)benzenamine
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| Drug Type |
Small molecular drug
|
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| Indication | Discovery agent | Investigative | [527907] | ||
| Formula |
C17H15NOS
|
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| Canonical SMILES |
COC1=CC=C(C=C1)C2=CC=C(S2)C3=CC=C(C=C3)N
|
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| InChI |
1S/C17H15NOS/c1-19-15-8-4-13(5-9-15)17-11-10-16(20-17)12-2-6-14(18)7-3-12/h2-11H,18H2,1H3
|
||||
| InChIKey |
JJUWIYUCBOADAD-UHFFFAOYSA-N
|
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Amyloid beta A4 protein | Target Info | Inhibitor | [527907] | |
| KEGG Pathway | Notch signaling pathway | ||||
| Alzheimer's disease | |||||
| Reactome | Nuclear signaling by ERBB4 | ||||
| Degradation of the extracellular matrix | |||||
| Regulated proteolysis of p75NTR | |||||
| NRIF signals cell death from the nucleus | |||||
| Activated NOTCH1 Transmits Signal to the Nucleus | |||||
| Constitutive Signaling by NOTCH1 PEST Domain Mutants | |||||
| Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants | |||||
| EPH-ephrin mediated repulsion of cells | |||||
| References | |||||
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