Drug Information

Drug General Information
Drug ID
D0V9KF
Former ID
DNC005082
Drug Name
8-(3,3,3-trifluoropropoxy)quinolin-2-amine
Drug Type
Small molecular drug
Indication Discovery agent Investigative [527194]
Formula
C12H11F3N2O
Canonical SMILES
C1=CC2=C(C(=C1)OCCC(F)(F)F)N=C(C=C2)N
InChI
1S/C12H11F3N2O/c13-12(14,15)6-7-18-9-3-1-2-8-4-5-10(16)17-11(8)9/h1-5H,6-7H2,(H2,16,17)
InChIKey
ZGZSZXFSLMTFBX-UHFFFAOYSA-N
PubChem Compound ID
22254540
Target and Pathway
Target(s) Melanin-concentrating hormone receptor 1 Target Info Inhibitor [527194]
KEGG Pathway Neuroactive ligand-receptor interaction
Reactome Peptide ligand-binding receptors
G alpha (q) signalling events
G alpha (i) signalling events
WikiPathways GPCRs, Class A Rhodopsin-like
Gastrin-CREB signalling pathway via PKC and MAPK
GPCR ligand binding
GPCR downstream signaling
References
Ref 527194Bioorg Med Chem Lett. 2004 Oct 4;14(19):4873-7.Synthesis and evaluation of 2-amino-8-alkoxy quinolines as MCHr1 antagonists. Part 1.
Ref 527194Bioorg Med Chem Lett. 2004 Oct 4;14(19):4873-7.Synthesis and evaluation of 2-amino-8-alkoxy quinolines as MCHr1 antagonists. Part 1.

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