Drug Information

Drug General Information
Drug ID
D0E0HK
Former ID
DNC003940
Drug Name
2-Mercaptomethyl-pentanedioic acid
Drug Type
Small molecular drug
Indication Discovery agent Investigative [526615]
Formula
C6H10O4S
Canonical SMILES
C(CC(=O)O)C(CS)C(=O)O
InChI
1S/C6H10O4S/c7-5(8)2-1-4(3-11)6(9)10/h4,11H,1-3H2,(H,7,8)(H,9,10)
InChIKey
LDFDXRPEWZHIML-UHFFFAOYSA-N
PubChem Compound ID
129558
Target and Pathway
Target(s) Glutamate carboxypeptidase II Target Info Inhibitor [526615]
KEGG Pathway Alanine, aspartate and glutamate metabolism
Metabolic pathways
Vitamin digestion and absorption
NetPath Pathway TCR Signaling Pathway
TNFalpha Signaling Pathway
Reactome Amino acid synthesis and interconversion (transamination)
WikiPathways One Carbon Metabolism
References
Ref 526615J Med Chem. 2003 May 8;46(10):1989-96.Synthesis and biological evaluation of thiol-based inhibitors of glutamate carboxypeptidase II: discovery of an orally active GCP II inhibitor.
Ref 526615J Med Chem. 2003 May 8;46(10):1989-96.Synthesis and biological evaluation of thiol-based inhibitors of glutamate carboxypeptidase II: discovery of an orally active GCP II inhibitor.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Tang and Dr. Zhang.