Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0I9NH
|
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| Former ID |
DNC006482
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| Drug Name |
5-hydroxy-2-(4-aminophenyl)benzofuran
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent | Investigative | [528159] | ||
| Formula |
C14H11NO2
|
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| Canonical SMILES |
C1=CC(=CC=C1C2=CC3=C(O2)C=CC(=C3)O)N
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| InChI |
1S/C14H11NO2/c15-11-3-1-9(2-4-11)14-8-10-7-12(16)5-6-13(10)17-14/h1-8,16H,15H2
|
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| InChIKey |
JDGXRZSZWVUFMN-UHFFFAOYSA-N
|
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Amyloid beta A4 protein | Target Info | Inhibitor | [528159] | |
| KEGG Pathway | Notch signaling pathway | ||||
| Alzheimer's disease | |||||
| Reactome | Nuclear signaling by ERBB4 | ||||
| Degradation of the extracellular matrix | |||||
| Regulated proteolysis of p75NTR | |||||
| NRIF signals cell death from the nucleus | |||||
| Activated NOTCH1 Transmits Signal to the Nucleus | |||||
| Constitutive Signaling by NOTCH1 PEST Domain Mutants | |||||
| Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants | |||||
| EPH-ephrin mediated repulsion of cells | |||||
| References | |||||
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