TTD | Drug: D00XGW

Drug General Information
Drug ID	D00XGW
Former ID	DIB019038
Drug Name	BVT173187
Synonyms	BVT 173187
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[541144]
Formula	C14H10Cl3NO2
InChI	InChI=1S/C14H10Cl3NO2/c1-7-2-3-10(16)12(4-7)18-14(20)9-5-8(15)6-11(17)13(9)19/h2-6,19H,1H3,(H,18,20)
InChIKey	UCOQCHLODZCXRH-UHFFFAOYSA-N
PubChem Compound ID	73755160
PubChem Substance ID	178102450
Target and Pathway
Target(s)	FMLP receptor	Target Info	Antagonist	[531840]
KEGG Pathway	Rap1 signaling pathway
	Neuroactive ligand-receptor interaction
	Staphylococcus aureus infection
NetPath Pathway	Leptin Signaling Pathway
PANTHER Pathway	Inflammation mediated by chemokine and cytokine signaling pathway
Pathway Interaction Database	Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
Reactome	G alpha (i) signalling events
WikiPathways	GPCRs, Class A Rhodopsin-like
	Human Complement System
	Peptide GPCRs
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 541144	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5825).
Ref 531840	A non-peptide receptor inhibitor with selectivity for one of the neutrophil formyl peptide receptors, FPR 1. Biochem Pharmacol. 2012 Jun 15;83(12):1655-62.

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Drug Information