Target Information

Target General Infomation
Target ID
T94594
Former ID
TTDR01157
Target Name
Probable nicotinate-nucleotide adenylyltransferase
Gene Name
nadD
Synonyms
Deamido-NAD(+) diphosphorylase; Deamido-NAD(+) pyrophosphorylase; NaMN AT; NaMN adenylyltransferase; NaMN-Atase; Nicotinate-nucleotide adenylyltransferase; Nicotinatemononucleotide adenylyltransferase; Nicotinic acid mononucleotide adenylyltransferase; nadD
Target Type
Research
Function
Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
BioChemical Class
Kinase
UniProt ID
Q9HX21
EC Number
EC 2.7.7.18
Sequence
MGKRIGLFGGTFDPVHIGHMRSAVEMAEQFALDELRLLPNARPPHRETPQVSAAQRLAMV
ERAVAGVERLTVDPRELQRDKPSYTIDTLESVRAELAADDQLFMLIGWDAFCGLPTWHRW
EALLDHCHIVVLQRPDADSEPPESLRDLLAARSVADPQALKGPGGQITFVWQTPLAVSAT
QIRALLGAGRSVRFLVPDAVLNYIEAHHLYRAPH
Inhibitor Deamido-Nad+ Drug Info [551393]
Nicotinamide-Adenine-Dinucleotide Drug Info [551393]
Pathways
KEGG Pathway Nicotinate and nicotinamide metabolism
Metabolic pathways
References
Ref 551393How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.

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