Drug Information

Drug General Information
Drug ID
D0ZX0Y
Former ID
DNC007846
Drug Name
4-hexylphenyl propiolate
Drug Type
Small molecular drug
Indication Discovery agent Investigative [529081]
Formula
C15H18O2
Canonical SMILES
CCCCCCC1=CC=C(C=C1)OC(=O)C#C
InChI
1S/C15H18O2/c1-3-5-6-7-8-13-9-11-14(12-10-13)17-15(16)4-2/h2,9-12H,3,5-8H2,1H3
InChIKey
IAEVDNHEIHTNJR-UHFFFAOYSA-N
PubChem Compound ID
23635856
Target and Pathway
Target(s) Thyroid hormone receptor beta-1 Target Info Inhibitor [529081]
Thyroid hormone receptor alpha Target Info Inhibitor [529081]
KEGG Pathway Neuroactive ligand-receptor interaction
Thyroid hormone signaling pathwayhsa04080:Neuroactive ligand-receptor interaction
Thyroid hormone signaling pathway
Pathway Interaction Database RXR and RAR heterodimerization with other nuclear receptorrxr_vdr_pathway:RXR and RAR heterodimerization with other nuclear receptor
Reactome Nuclear Receptor transcription pathwayR-HSA-383280:Nuclear Receptor transcription pathway
WikiPathways SIDS Susceptibility Pathways
Hematopoietic Stem Cell Differentiation
Nuclear ReceptorsWP474:Endochondral Ossification
Nuclear Receptors
References
Ref 529081J Med Chem. 2007 Nov 1;50(22):5269-80. Epub 2007 Oct 5.Inhibitors of the interaction of a thyroid hormone receptor and coactivators: preliminary structure-activity relationships.
Ref 529081J Med Chem. 2007 Nov 1;50(22):5269-80. Epub 2007 Oct 5.Inhibitors of the interaction of a thyroid hormone receptor and coactivators: preliminary structure-activity relationships.

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