Drug Information

Drug General Information
Drug ID
D0ZL9B
Former ID
DIB011352
Drug Name
Diaspirin crosslinked hemoglobin
Synonyms
DCLHb; HemAssist; DCLHb, Baxter; Diaspirin crosslinked hemoglobin, Baxter
Indication Cerebrovascular ischaemia [ICD9: 434.91; ICD10:I61-I63] Terminated [545936]
Company
Baxter Healthcare Ltd
CAS Number
CAS 142261-03-8
Target and Pathway
Target(s) Hemoglobin Target Info Modulator [530709]
KEGG Pathway African trypanosomiasis
Malaria
Reactome Erythrocytes take up carbon dioxide and release oxygen
Erythrocytes take up oxygen and release carbon dioxide
Scavenging of heme from plasma
WikiPathways Binding and Uptake of Ligands by Scavenger Receptors
Uptake of Carbon Dioxide and Release of Oxygen by Erythrocytes
Uptake of Oxygen and Release of Carbon Dioxide by Erythrocytes
Factors involved in megakaryocyte development and platelet production
Folate Metabolism
Vitamin B12 Metabolism
Selenium Micronutrient Network
References
Ref 545936Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800005412)
Ref 530709Diaspirin cross-linked hemoglobin infusion did not influence base deficit and lactic acid levels in two clinical trials of traumatic hemorrhagic shock patient resuscitation. J Trauma. 2010 May;68(5):1158-71.

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