Drug Information

Drug General Information
Drug ID
D0ZF1W
Former ID
DIB020473
Drug Name
N-1-isopropyltryptamine
Drug Type
Small molecular drug
Indication Discovery agent Investigative [538967]
Formula
C13H18N2
InChI
InChI=1S/C13H18N2/c1-10(2)15-9-11(7-8-14)12-5-3-4-6-13(12)15/h3-6,9-10H,7-8,14H2,1-2H3
InChIKey
ARHHZLRATAUACE-UHFFFAOYSA-N
PubChem Compound ID
5115445
PubChem Substance ID
7584375, 8565199, 15092283, 26080005, 38738045, 57724641, 78722307, 88831625, 104824632, 113745845, 127447981, 135650393, 136351043, 143450085, 170182221, 233328137
Target and Pathway
Target(s) 5-hydroxytryptamine 2A receptor Target Info Agonist [533905]
KEGG Pathway Calcium signaling pathway
Neuroactive ligand-receptor interaction
Gap junction
Serotonergic synapse
Inflammatory mediator regulation of TRP channels
PANTHER Pathway 5HT2 type receptor mediated signaling pathway
Reactome Serotonin receptors
G alpha (q) signalling events
WikiPathways Serotonin Receptor 2 and STAT3 Signaling
Serotonin Receptor 2 and ELK-SRF/GATA4 signaling
SIDS Susceptibility Pathways
Monoamine GPCRs
GPCRs, Class A Rhodopsin-like
Gastrin-CREB signalling pathway via PKC and MAPK
GPCR ligand binding
GPCR downstream signaling
GPCRs, Other
References
Ref 538967(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 159).
Ref 533905Species variations in transmembrane region V of the 5-hydroxytryptamine type 2A receptor alter the structure-activity relationship of certain ergolines and tryptamines. Mol Pharmacol. 1994 Feb;45(2):277-86.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Tang and Dr. Zhang.