Drug Information

Drug General Information
Drug ID
D0Z5HB
Former ID
DIB009972
Drug Name
FH-510
Drug Type
Small molecular drug
Indication Psychotic disorders [ICD9: 290-299; ICD10:F20-F29] Terminated [545084]
Company
Taisho Pharmaceutical Co Ltd
Formula
C22H31ClN2
Canonical SMILES
[nH]1c2c(c3c1cccc3CCN(CCC)CCC)c(ccc2C)C.Cl
CAS Number
CAS 139304-28-2
PubChem Compound ID
135554
Target and Pathway
Target(s) Sigma(1)-type opioid receptor Target Info Modulator [526642], [532713], [533898]
WikiPathways miR-targeted genes in squamous cell - TarBase
miR-targeted genes in lymphocytes - TarBase
References
Ref 545084Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800002069)
Ref 526642Dextromethorphan antagonizes the acute depletion of brain serotonin by p-chloroamphetamine and H75/12 in rats. Brain Res. 1992 Oct 30;594(2):323-6.
Ref 532713Antitussives and substance abuse. Subst Abuse Rehabil. 2013 Nov 6;4:75-82.
Ref 533898FH-510, a potent and selective ligand for rat brain sigma recognition sites. Eur J Pharmacol. 1993 Jul 6;238(1):89-92.

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