Drug Information

Drug General Information
Drug ID
D0Z2UT
Former ID
DIB003038
Drug Name
BNP-FIX
Synonyms
BNP-FIX; Gene therapy (BNP, hemophilia B); Biological Nano Particles-Factor IX (hemophilia B), Asklepios; Gene therapy (BNP, hemophilia B), Asklepios; Gene therapy (hemophilia B), Asklepios/Bayer
Indication Factor IX deficiency [ICD10:D67] Investigative [543608]
Company
Asklepios Biopharmaceutical Inc
Target and Pathway
Target(s) Coagulation factor IX Target Info Modulator [543608]
KEGG Pathway Complement and coagulation cascades
PANTHER Pathway Blood coagulation
PathWhiz Pathway Coagulation
Reactome Extrinsic Pathway of Fibrin Clot Formation
Intrinsic Pathway of Fibrin Clot Formation
Gamma-carboxylation of protein precursors
Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus
Removal of aminoterminal propeptides from gamma-carboxylated proteins
WikiPathways Complement and Coagulation Cascades
PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
Blood Clotting Cascade
Formation of Fibrin Clot (Clotting Cascade)
References
Ref 543608(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 2364).
Ref 543608(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 2364).

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