Drug Information

Drug General Information
Drug ID
D0XW9U
Former ID
DNC014067
Drug Name
N-methyl-2-(pyridin-2-yl)ethanamine
Drug Type
Small molecular drug
Indication Discovery agent Investigative [530151]
Formula
C8H12N2
Canonical SMILES
CNCCC1=CC=CC=N1
InChI
1S/C8H12N2/c1-9-7-5-8-4-2-3-6-10-8/h2-4,6,9H,5,7H2,1H3
InChIKey
UUQMNUMQCIQDMZ-UHFFFAOYSA-N
PubChem Compound ID
2366
Target and Pathway
Target(s) Histamine H3 receptor Target Info Inhibitor [530151]
KEGG Pathway Neuroactive ligand-receptor interaction
Reactome Histamine receptors
G alpha (i) signalling events
WikiPathways Monoamine Transport
GPCRs, Class A Rhodopsin-like
GPCR ligand binding
GPCR downstream signaling
References
Ref 530151J Med Chem. 2009 Jul 9;52(13):3855-68.5-hydroxyindole-2-carboxylic acid amides: novel histamine-3 receptor inverse agonists for the treatment of obesity.
Ref 530151J Med Chem. 2009 Jul 9;52(13):3855-68.5-hydroxyindole-2-carboxylic acid amides: novel histamine-3 receptor inverse agonists for the treatment of obesity.

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