Drug Information

Drug General Information
Drug ID
D0X9PW
Former ID
DIB006862
Drug Name
Tesmilifene
Synonyms
DPPE; DPPE hydrocloride; Tesmilifene hydrochloride; BMS 217380-01; BMS-217380; BMY-33419; DPPE, BMS; YMB-1002; Anticancer, BMS/Manitoba Univ/MTCR
Drug Type
Small molecular drug
Indication Breast cancer; Prostate cancer [ICD9: 174, 175, 185; ICD10:C50, C61] Discontinued in Phase 2 [545850]
Company
YM Biosciences
Formula
C19H25NO
Canonical SMILES
c1(Cc2ccccc2)ccc(cc1)OCCN(CC)CC
PubChem Compound ID
108092
Target and Pathway
Target(s) Histamine receptor Target Info Modulator [531060]
References
Ref 545850Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800005041)
Ref 531060Effects of tesmilifene, a substrate of CYP3A and an inhibitor of P-glycoprotein, on the pharmacokinetics of intravenous and oral docetaxel in rats. J Pharm Pharmacol. 2010 Aug;62(8):1084-8.

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